Aura Biosciences

First pharmacological treatment for ocular melanoma

Aura is developing a first-in-class treatment for ocular melanoma and other ocular cancers based on a photo-activatable dye conjugated to HPV-derived nanoparticles that target tumour cells in the eye.

Aura’s lead product will enter clinical testing in early 2017. It is potentially the first alternative to the current treatment options of either radiotherapy or enucleation.

CEO  Elisabet de los Pinos

Advent Contact  Raj Parekh

Advent invested in the Series B in 2015.
Publicly Listed
13 November 2024 in Aura Biosciences, Press Release, Private Companies

Aura Biosciences Reports Third Quarter 2024 Financial Results and Business Highlights

Press Release.   Positive Phase 2 End of Study Data with Bel-sar in Early-Stage Choroidal Melanoma; Ongoing Phase 3 CoMpass Trial Recently Received Authorization to Start Enrolling Patients in Europe Multiple…
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18 October 2024 in Aura Biosciences, Press Release, Private Companies

Multiple Clinical Complete Responses Demonstrated Following Single Low Dose Administration of Bel-sar in Patients with Non-Muscle-Invasive Bladder Cancer (NMIBC) in Ongoing Phase 1 Trial

Press Release.   Multiple Clinical Complete Responses Demonstrated Following Single Low Dose Administration of Bel-sar in Patients with Non-Muscle-Invasive Bladder Cancer (NMIBC) in Ongoing Phase 1 Trial October 17, 2024…
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12 September 2024 in Aura Biosciences, Press Release, Private Companies

Aura Biosciences Reports Positive Phase 2 End of Study Results Evaluating Bel-sar as a First-Line Treatment for Early-Stage Choroidal Melanoma

Press Release.   Aura Biosciences Reports Positive Phase 2 End of Study Results Evaluating Bel-sar as a First-Line Treatment for Early-Stage Choroidal Melanoma Bel-sar Demonstrated 80% Tumor Control Rate, 90%…
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7 December 2023 in Aura Biosciences, Press Release, Private Companies

Aura Biosciences Announces First Patient Dosed in Global Phase 3 CoMpass Trial

Press Release.   Aura Biosciences Announces First Patient Dosed in Global Phase 3 CoMpass Trial Evaluating the Safety and Efficacy of Belzupacap Sarotalocan (Bel-sar) for First-Line Treatment of Early-Stage Choroidal…
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6 November 2023 in Aura Biosciences, Press Release, Private Companies

Aura Biosciences Receives FDA Agreement for CoMpass Phase 3 Clinical Trial

Press Release.   Aura Biosciences Receives FDA Agreement Under Special Protocol Assessment (SPA) for CoMpass Phase 3 Clinical Trial of Belzupacap Sarotalocan (Bel-sar) in Early-stage Choroidal Melanoma November 6, 2023…
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29 March 2023 in Aura Biosciences, Press Release, Private Companies, Publicly Listed

Eloxx Pharmaceuticals Announces Submission of Investigational New Drug (IND) Application for ZKN-013

Press Release.   ZKN-013 in development for treatment of recessive dystrophic epidermolysis bullosa (RDEB) and junctional epidermolysis bullosa (JEB) Additional IND filing for ZKN-013 for treatment of familial adenomatous polyposis…
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16 February 2023 in Aura Biosciences, Press Release, Private Companies, Publicly Listed

Aura Biosciences Announces Positive Interim Phase 2 Safety and Efficacy Data of Belzupacap Sarotalocan (Bel-sar) for the First-Line Treatment of Patients with Early-Stage Choroidal Melanoma with Suprachoroidal Administration

Press Release.   Aura Biosciences Announces Positive Interim Phase 2 Safety and Efficacy Data of Belzupacap Sarotalocan (Bel-sar) for the First-Line Treatment of Patients with Early-Stage Choroidal Melanoma with Suprachoroidal…
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1 December 2022 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Announces Pricing of Public Offering of Common Stock

Press Release. BOSTON--(BUSINESS WIRE)-- Aura Biosciences, Inc. (“Aura”) (Nasdaq: AURA), a clinical-stage biotechnology company developing a novel class of virus-like drug conjugate (VDC) therapies for multiple oncology indications, today announced…
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10 November 2022 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Reports Third Quarter 2022 Financial Results and Provides Clinical Development and Operational Highlights

Press Release. Announced the Global Phase 3 Trial Design with Suprachoroidal Route of Administration of Belzupacap Sarotalocan in Early-Stage Choroidal Melanoma First Patient Dosed in the Phase 1 Study Evaluating…
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10 November 2022 in Aura Biosciences, Press Release, Publicly Listed

Aura Announces Global Phase 3 Trial Design with Suprachoroidal Route of Administration Based on Positive Phase 2 Interim Data of Belzupacap Sarotalocan in Early-Stage Choroidal Melanoma

Press Release.   BOSTON, MA – November 10, 2022 – Aura Biosciences Inc. (NASDAQ: AURA), a clinical-stage biotechnology company developing a novel class of virus-like drug conjugate (VDC) therapies for…
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3 October 2022 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Announces Interim Phase 2 Data Evaluating Suprachoroidal Administration of Belzupacap Sarotalocan (AU-011) for the First-Line Treatment of Patients with Early-Stage Choroidal Melanoma Presented at AAO 2022

Press Release.   BOSTON - (BUSINESS WIRE) - Oct. 3, 2022 - Aura Biosciences Inc. (NASDAQ: AURA), a clinical-stage biotechnology company developing a novel class of virus-like drug conjugate (VDC)…
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28 September 2022 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Announces First Patient Dosed in Phase 1 Study Evaluating Belzupacap Sarotalocan (AU-011) for the Treatment of Non-Muscle Invasive Bladder Cancer

Press Release.   BOSTON - (BUSINESS WIRE) 28.09.2022 - Aura Biosciences Inc. (NASDAQ: AURA), a clinical-stage biotechnology company developing a novel class of virus-like drug conjugate (VDC) therapies for multiple…
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1 July 2022 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Receives FDA Fast Track Designation for Belzupacap Sarotalocan (AU-011) for the Treatment of Non-Muscle Invasive Bladder Cancer

Press Release.   CAMBRIDGE, Mass. -- (BUSINESS WIRE) -- Aura Biosciences, Inc. (NASDAQ: AURA), a clinical-stage biotechnology company developing a novel class of virus-like drug conjugate (VDC) therapies for multiple…
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26 May 2022 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Announces Publication of Preclinical Data of the Combination of VDCs with Immune Checkpoint Inhibitors at the 2022 ASCO Annual Meeting

Press Release.   CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Aura Biosciences Inc. (NASDAQ: AURA), a clinical-stage biotechnology company developing a novel class of virus-like drug conjugate (VDC) therapies for multiple oncology indications, today…
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3 May 2022 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Presents Preclinical Data Highlighting AU-011’s Anti-Tumor Activity in Choroidal Metastasis, an Additional Ocular Oncology Indication at the 2022 ARVO Annual Meeting

Press Release.   Preclinical studies support further development of AU-011 for choroidal metastasis CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Aura Biosciences Inc. (NASDAQ: AURA), a clinical-stage biotechnology company developing a novel class of…
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9 March 2022 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences to Present Preclinical Data Highlighting AU 011’s Potential to Target a Broad Number of Tumor Types at the 2022 AACR Annual Meeting

Press Release.   CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Aura Biosciences Inc. (NASDAQ: AURA), a clinical-stage biotechnology company developing a novel class of virus-like drug conjugate (VDC) therapies for multiple oncology indications, today…
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15 November 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Presents Final Phase 1b/2 Data for its first Virus-Like Drug Conjugate, AU-011, in Patients with Choroidal Melanoma at the American Academy of Ophthalmology

Press Release.   Aura Biosciences Presents Final Phase 1b/2 Data for its first Virus-Like Drug Conjugate, AU-011, in Patients with Choroidal Melanoma at the American Academy of Ophthalmology 2021 Annual…
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28 October 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Announces Pricing of Initial Public Offering

Press Release.   October 28, 2021 09:39 PM Eastern Daylight Time CAMBRIDGE, Mass.--(BUSINESS WIRE)--Aura Biosciences, Inc. (“Aura”), a clinical-stage oncology company developing a novel class of virus-like drug conjugate therapies…
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11 October 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Presents Interim Phase 2 Safety Data Evaluating Suprachoroidal Administration of AU-011 in Patients with Choroidal Melanoma at the ASRS 2021 Annual Meeting

Press Release.   CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Aura Biosciences, a clinical-stage oncology company developing a novel class of virus-like drug conjugate (VDC) therapies for multiple oncology indications, today announced the presentation…
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29 September 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Expands Executive Leadership Team and Board of Directors

Press Release.   Chris Primiano, J.D., Appointed as Chief Business Officer Antony Mattessich Appointed to the Board of Directors CAMBRIDGE, MA - September 29,2021 - Aura Biosciences, a clinical-stage oncology…
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17 June 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Assembles New Bladder Cancer Focused Scientific Advisory Board

Press Release.   Prominent, Multi-Disciplinary Clinicians and Scientists Bring Extensive Strategic Expertise in Urologic Oncology Across All Stages of Research and Development CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Aura Biosciences, a clinical-stage oncology…
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8 June 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Appoints Sapna Srivastava, Ph.D., to its Board of Directors

Press Release.   June 08, 2021 07:00 AM Eastern Daylight Time CAMBRIDGE, Mass.--(BUSINESS WIRE)--Aura Biosciences, a clinical-stage oncology company developing a novel class of virus-like drug conjugate (VDC) therapies for…
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14 April 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Announces Publication of Data in Cancer Immunology Research Supporting the Immune Mediated Mechanism of Action of the Virus-Like Drug Conjugate (VDC) Technology Platform with Broad Application in Cancer Treatment

Press Release.   Results Support VDCs induction of Pro Immunogenic Cell Death and the Generation of Long Lasting Adaptive Anti-Tumor Immunity - Combination of VDCs with Checkpoint Inhibitors Achieves a…
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24 March 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Expands Executive Leadership Team with the Appointment of Mark De Rosch, Ph.D., as Chief Operating Officer

Press Release.   March 24, 2021 CAMBRIDGE, MA – March 24, 2021 – Aura Biosciences, a clinical-stage oncology company developing a novel class of virus-like drug conjugate (VDC) therapies for…
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18 March 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Announces Oversubscribed $80 Million Financing

Press Release.   Proceeds to Support Pivotal Program of AU-011 for the First Line Treatment of Choroidal Melanoma and Expansion of Virus-like Drug Conjugate (VDC) Platform in additional Ocular Oncology…
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5 January 2021 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Appoints David Johnson to Its Board of Directors

Press Release.   CAMBRIDGE, MA –January 5th, 2021– Aura Biosciences, a clinical-stage oncology company developing a novel class of drug conjugate therapies for multiple oncology indications, today announced the appointment…
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2 April 2019 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Completes $40 Million Series D Financing

Press Release.   CAMBRIDGE, MA – April 2, 2019 – Aura Biosciences, a leader in the development of novel targeted therapies in ocular oncology, today announced that it closed a…
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21 December 2017 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Completes $30 Million Series C Financing

Press Release.   December 21, 2017 Lead candidate, light-activated AU-011, currently being investigated in Phase 1b/2 study to treat ocular melanoma, an orphan indication Funding to support ongoing clinical development,…
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29 September 2016 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Secures $8 Million in Additional Funding

Press Release.   Aura Biosciences Secures $8 Million in Additional Funding and Augments Board of Directors and Clinical Advisory Board September 29, 2016 Proceeds will support clinical development of the…
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5 March 2015 in Aura Biosciences, Press Release, Publicly Listed

Aura Biosciences Closes $21M Series B Financing

Press Release.   Prepares to enter clinical trials for the treatment of rare ocular cancers CAMBRIDGE, MASSACHUSETTS – March 5, 2015 – Aura Biosciences, a biotech company developing highly tumor-targeted…
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